– perennial herbaceous plant Fritillaria cirrhosa D. Don or F. unibracteata Hsiao et K. C. Hsia or F. przewalskii Maxim or F. delavayi Franch. of family Lilium.
– Sichuan, Yunnan and Gansu provinces in China.
Bulbus fritillariae cirrhosae(chin. : 川贝母)
– the bulb of Fritillaria genus from the Liliaceae (or Lilly) family, called Fritillaria cirrhosa.
– It is used in Chinese herbology, for example in the Baihe Gujin Wan, to “nourish yin of the lung, resolve phlegm and relieve cough
– known for their remarkable efficacy on moistening lung to arrest cough
remove stasis to reduce swelling.
– Its main indications and uses are irritating dry cough caused by lung heat, hacking cough with little phlegm, cough due to overexertion and Yin deficiency,
– dry coughing and sputum with blood,
– stagnation in chest and heart,
– the consumptive lung disease,
– pulmonary abscess, pharyngitis, and acute mastitis
– Both fritillaria alkaloids and non-alkaloids have antitussive function;
– Both fritillary liquid extract and fritimine have expectorant effects, but in varying degrees;
– Sipeimine is antispasmodic;
– Both Fritimine and Imperialine can lower blood pressure;
– Peimine can increase uterine tension;
– The total alkaloids from Fritillaria have anti-ulcer effect
– Fritillaria ussuriensis (FU, derived from the bulbs of various species of the genus Fritillaria, including Fritillaria thunbergii Miq) has shown significant inhibition of mast-cell accumulation in ear tissue at the chronic phase.
– These results indicate that it inhibits allergic reactions, according to the study of “Fritillaria ussuriensis extract inhibits the production of inflammatory cytokine and MAPKs in mast cells” by Cho IH, Lee MJ, Kim JH, Han NY, Shin KW, Sohn Y, Jung HS